{"id":590,"date":"2026-08-20T17:05:08","date_gmt":"2026-08-20T15:05:08","guid":{"rendered":"https:\/\/4beauty-website-stage.247grad.de\/glossar\/biofiller\/"},"modified":"2026-08-28T11:45:23","modified_gmt":"2026-08-28T09:45:23","slug":"biofiller","status":"publish","type":"glossary","link":"https:\/\/4beauty-website-stage.247grad.de\/en\/glossar\/biofiller\/","title":{"rendered":"Biofiller"},"content":{"rendered":"<div class=\"wp-block-rank-math-toc-block\" id=\"rank-math-toc\"><h2>Table of Contents<\/h2><nav><ul><li class=\"\"><a href=\"#definition-was-ist-ein-biofiller\">Definition: What is a biofiller?<\/a><\/li><li class=\"\"><a href=\"#wie-wird-der-biofiller-hergestellt-der-ablauf-in-3-schritten\">How is the biofiller produced? The process in 3 steps<\/a><\/li><li class=\"\"><a href=\"#wie-wirkt-der-biofiller-in-der-haut\">How does the biofiller work in the skin?<\/a><\/li><li class=\"\"><a href=\"#biofiller-vs-hyaluronsaure-ein-kritischer-vergleich\">Biofillers vs. hyaluronic acid: a critical comparison<\/a><\/li><li class=\"\"><a href=\"#anwendungsbereiche-und-grenzen-der-behandlung\">Areas of application and limitations of the treatment<\/a><\/li><li class=\"\"><a href=\"#risiken-nebenwirkungen-wenn-naturlich-nicht-risikofrei-bedeutet\">Risks &amp; Side Effects: When \u201enatural\u201c does not mean risk-free<\/a><\/li><li class=\"\"><a href=\"#was-kostet-eine-behandlung-mit-biofiller\">How much does a Biofiller treatment cost?<\/a><\/li><li class=\"\"><a href=\"#haufig-gestellte-fragen-faq-zum-biofiller\">Frequently Asked Questions (FAQ) about Biofiller<\/a><\/li><\/ul><\/nav><\/div>\n\n\n\n<div class=\"wp-block-group is-style-boxed has-white-warm-background-color has-background is-layout-constrained wp-block-group-is-layout-constrained\">\n<p class=\"wp-block-paragraph\"><strong>Important note<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This article is for information purposes only and is not a substitute for a medical diagnosis or advice. If you are unsure, or if you require a personalised treatment plan, it is essential that you consult a qualified specialist.<\/p>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">The desire for a natural look and treatments that are in harmony with one\u2019s own body is a growing trend in aesthetic medicine. In this context, so-called \u2018biofillers\u2019, also known as plasma fillers, are becoming increasingly popular. They promise to treat wrinkles and restore volume. The gel is derived entirely from the patient\u2019s own blood and contains no synthetic additives.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">But how exactly does this method work, what can it achieve and \u2013 most importantly \u2013 how safe is it really? In our glossary entry, we take an objective look at the biofiller, explain the process and provide you with a realistic assessment of the benefits and risks.<\/p>\n\n\n\n<div class=\"wp-block-media-text is-stacked-on-mobile\"><figure class=\"wp-block-media-text__media\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller.png\" alt=\"Treatment with a biofiller\" class=\"wp-image-384 size-full\" srcset=\"https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller.png 1024w, https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller-150x150.png 150w, https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller-300x300.png 300w, https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller-768x768.png 768w, https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller-12x12.png 12w, https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller-120x120.png 120w, https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller-40x40.png 40w, https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller-80x80.png 80w, https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller-160x160.png 160w, https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller-500x500.png 500w, https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller-1000x1000.png 1000w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure><div class=\"wp-block-media-text__content\">\n<h2 class=\"wp-block-heading\" id=\"definition-was-ist-ein-biofiller\">Definition: What is a biofiller?<\/h2>\n\n<p class=\"wp-block-paragraph\">A <strong>Biofiller<\/strong>, also <strong>Plasma filler<\/strong> or <strong>PRF filler<\/strong> known as, is a gel-like filler derived entirely from the patient\u2019s own blood. A special process is used to produce a gel from the blood plasma, which is rich in blood platelets (thrombocytes) and growth factors.<\/p>\n\n<p class=\"wp-block-paragraph\">This autologous gel is then used in the same way as a conventional dermal filler to <a href=\"https:\/\/4beauty-website-stage.247grad.de\/en\/glossary\/injection\/\">Injection<\/a> used to treat wrinkles, add volume or improve skin quality.<\/p>\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/4beauty-website-stage.247grad.de\/en\/service-information\/contact\/\">Contact us for a no-obligation enquiry<\/a><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"wie-wird-der-biofiller-hergestellt-der-ablauf-in-3-schritten\">How is the biofiller produced? The process in 3 steps<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The biofiller is prepared directly at the practice immediately before the treatment and usually takes around 30 to 45 minutes.<\/p>\n\n\n\n<ol class=\"wp-block-list is-style-step-list\">\n<li><strong>Step 1: Blood sample collection<\/strong> A small amount of blood is taken from the patient\u2019s arm vein, much like a normal blood test at the GP\u2019s surgery.<\/li>\n\n\n\n<li><strong>Step 2: Centrifugation and processing<\/strong> The blood is placed in special tubes and put into a centrifuge. The rapid rotation causes the blood components to separate: the red blood cells settle at the bottom, whilst the pale yellow blood plasma remains at the top. For the biofiller, platelet-rich fibrin (PRF) is obtained through a specialised centrifugation process, which creates a fibrin coagulation network containing platelets and growth factors.<\/li>\n\n\n\n<li><strong>Step 3: Preparing the gel and administering the injection<\/strong> The PRF coagulation network obtained is transformed, through a controlled process, into a gel-like, injectable consistency which can be liquefied by the body\u2019s own heat or, if necessary, by gentle heating. The treating doctor or alternative practitioner can then inject this finished plasma gel into the desired areas using fine needles.<\/li>\n<\/ol>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1396\" src=\"https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller-herstellung-scaled.png\" alt=\"Manufacturing process for the biofiller\" class=\"wp-image-383\" srcset=\"https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller-herstellung-scaled.png 2560w, https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller-herstellung-1024x559.png 1024w, https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller-herstellung-300x164.png 300w, https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller-herstellung-768x419.png 768w, https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller-herstellung-1536x838.png 1536w, https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller-herstellung-2048x1117.png 2048w, https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller-herstellung-18x10.png 18w, https:\/\/4beauty-website-stage.247grad.de\/wp-content\/uploads\/2026\/08\/2026-01_biofiller-herstellung-40x22.png 40w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"wie-wirkt-der-biofiller-in-der-haut\">How does the biofiller work in the skin?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>1. Instant volume effect:<\/strong> The injected gel immediately fills in wrinkles and areas of volume loss, much like a hyaluronic acid filler. The immediate volumising effect is temporary, as the body breaks down the gel after a few months. However, the biostimulating effect on collagen production lasts longer.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>2. Biostimulation:<\/strong> This is the key, long-term effect. The growth factors, which are highly concentrated in the PRF, stimulate the body\u2019s own regenerative processes and can encourage fibroblasts (connective tissue cells) to produce new collagen and elastin. However, the effectiveness varies from person to person.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"biofiller-vs-hyaluronsaure-ein-kritischer-vergleich\">Biofillers vs. hyaluronic acid: a critical comparison<\/h2>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>Characteristic<\/th><th>Biofiller (Plasma Filler)<\/th><th>Hyaluronic acid fillers<\/th><\/tr><\/thead><tbody><tr><td>Material<\/td><td>100 % autologous<\/td><td>Synthesised, but identical to natural substances<\/td><\/tr><tr><td>Compatibility<\/td><td>Excellent, no allergic reactions<\/td><td>Very good; allergies are extremely rare<\/td><\/tr><tr><td>Mode of action<\/td><td>Volume + Biostimulation (collagen production)<\/td><td>Primarily volume &amp; moisture retention<\/td><\/tr><tr><td>Lifting capacity<\/td><td>Low, ideal for smooth transitions<\/td><td>High, ideal for contouring (chin, cheeks)<\/td><\/tr><tr><td>Result<\/td><td>Very natural, but harder to predict<\/td><td>Highly precise and predictable<\/td><\/tr><tr><td>Shelf life<\/td><td>3\u20136 months; regenerative effects last longer<\/td><td>6\u201318 months, depending on the product and region<\/td><\/tr><tr><td>Resolvability<\/td><td>Cannot be specifically resolved<\/td><td>Can be specifically broken down by the enzyme hylase<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"anwendungsbereiche-und-grenzen-der-behandlung\">Areas of application and limitations of the treatment<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Filling in mild to moderate wrinkles (e.g. <a href=\"https:\/\/4beauty-website-stage.247grad.de\/en\/glossary\/nasolabialfalte\/\">Nasolabial folds<\/a>)<\/li>\n\n\n\n<li>Treatment of dark circles and tear troughs<\/li>\n\n\n\n<li>Improvement in skin quality and firmness<\/li>\n\n\n\n<li>Natural, gentle volume enhancement in the cheeks<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Key limitations:<\/strong> For deep wrinkles or pronounced contouring (e.g. jawline, chin augmentation), hyaluronic acid fillers are often the better choice due to their greater stability and lifting capacity.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"risiken-nebenwirkungen-wenn-naturlich-nicht-risikofrei-bedeutet\">Risks &amp; Side Effects: When \u201enatural\u201c does not mean risk-free<\/h2>\n\n\n\n<div class=\"wp-block-group is-style-boxed is-layout-constrained wp-block-group-is-layout-constrained\">\n<p class=\"wp-block-paragraph\"><strong>Important safety information and risks<\/strong><\/p>\n\n<ul class=\"wp-block-list\">\n<li><strong>Common side effects:<\/strong> As with any injection, swelling, redness, mild pain and small bruises (<a href=\"https:\/\/4beauty-website-stage.247grad.de\/en\/glossary\/haematom\/\">Haematomas<\/a>) are normal and subside after a few days.<\/li>\n\n\n\n<li><strong>Process-related risks:<\/strong> The safety of the procedure depends entirely on maintaining sterile working practices, the quality of the equipment and the operator\u2019s experience. If hygiene standards are not met, there is a serious risk of infection, as the procedure involves the use of blood products.<\/li>\n\n\n\n<li><strong>Application risks:<\/strong> Improper injection by an inexperienced user can lead to asymmetry, nodule formation or uneven results.<\/li>\n\n\n\n<li><strong>Lack of long-term data:<\/strong> Compared with hyaluronic acid, which has been the subject of research for decades, the biofiller is a more recent method. Comprehensive long-term studies on its safety and efficacy have not yet been completed, but initial clinical findings show promising results.<\/li>\n<\/ul>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">It is therefore crucial to choose a qualified doctor or alternative practitioner with proven experience in autohaemotherapy.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The conclusion of a <a href=\"https:\/\/4beauty-website-stage.247grad.de\/en\/after-care-insurance\/\">Consequential Costs Insurance<\/a> can provide patients with additional peace of mind: it comes into effect if unexpected medical complications arise and the treatment incurs additional costs that are not covered by standard health insurance.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/4beauty-website-stage.247grad.de\/en\/service-information\/contact\/\">Contact us for a no-obligation enquiry<\/a><\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"was-kostet-eine-behandlung-mit-biofiller\">How much does a Biofiller treatment cost?<\/h2>\n\n\n\n<div class=\"wp-block-group is-style-boxed has-white-warm-background-color has-background is-layout-constrained wp-block-group-is-layout-constrained\">\n<p class=\"wp-block-paragraph\"><strong>Cost of a Biofiller treatment<\/strong><\/p>\n\n<p class=\"wp-block-paragraph\">The cost of a biofiller treatment is higher than that of a standard PRP therapy, as the preparation process is more complex. Costs vary depending on the clinic, the region and the quantity required.<\/p>\n\n<p class=\"wp-block-paragraph\">On average, you can expect costs of between <strong>\u20ac400 and \u20ac800 per session<\/strong> calculate.<\/p>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"haufig-gestellte-fragen-faq-zum-biofiller\">Frequently Asked Questions (FAQ) about Biofiller<\/h2>\n\n\n\n<div data-wp-context=\"{ &quot;autoclose&quot;: false, &quot;accordionItems&quot;: [] }\" data-wp-interactive=\"core\/accordion\" role=\"group\" class=\"wp-block-accordion is-layout-flow wp-block-accordion-is-layout-flow\">\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-1&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h3 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-1-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-1\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-title\">Is the treatment painful?<\/span><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><\/button><\/h3>\n\n\n\n<div aria-labelledby=\"accordion-item-1\" data-wp-bind--hidden=\"state.isHidden\" data-wp-on--beforematch=\"actions.handleBeforeMatch\" id=\"accordion-item-1-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p class=\"wp-block-paragraph\">Having your blood taken involves a quick prick. The injections themselves can feel uncomfortable, so an anaesthetic cream is usually applied to the skin beforehand.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-2&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h3 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-2-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-2\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-title\">What is the difference between this and a vampire facelift (PRP)?<\/span><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><\/button><\/h3>\n\n\n\n<div aria-labelledby=\"accordion-item-2\" data-wp-bind--hidden=\"state.isHidden\" data-wp-on--beforematch=\"actions.handleBeforeMatch\" id=\"accordion-item-2-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p class=\"wp-block-paragraph\">In a vampire facelift, liquid, platelet-rich plasma (PRP) is injected superficially into the skin or introduced via microneedling to improve skin quality. With the Biofiller treatment, the plasma (PRF) is processed into a thick gel which can also add volume.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-3&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h3 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-3-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-3\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-title\">How many treatments are needed?<\/span><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><\/button><\/h3>\n\n\n\n<div aria-labelledby=\"accordion-item-3\" data-wp-bind--hidden=\"state.isHidden\" data-wp-on--beforematch=\"actions.handleBeforeMatch\" id=\"accordion-item-3-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p class=\"wp-block-paragraph\">To achieve a visible and longer-lasting effect, 2\u20133 treatments at intervals of approximately 4\u20136 weeks are often recommended. After that, annual touch-ups are sufficient.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-4&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h3 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-4-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-4\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-title\">How long does the Biofiller last?<\/span><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><\/button><\/h3>\n\n\n\n<div aria-labelledby=\"accordion-item-4\" data-wp-bind--hidden=\"state.isHidden\" data-wp-on--beforematch=\"actions.handleBeforeMatch\" id=\"accordion-item-4-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p class=\"wp-block-paragraph\">The gel\u2019s immediate volumising effect lasts for around 3 to 6 months. However, the stimulating effect on collagen production and the associated improvement in skin condition lasts considerably longer.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-5&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h3 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-5-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-5\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-title\">Are there any people who must not be treated?<\/span><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><\/button><\/h3>\n\n\n\n<div aria-labelledby=\"accordion-item-5\" data-wp-bind--hidden=\"state.isHidden\" data-wp-on--beforematch=\"actions.handleBeforeMatch\" id=\"accordion-item-5-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p class=\"wp-block-paragraph\">Yes. Contraindications include, amongst others, blood clotting disorders, acute or chronic infectious diseases, cancers and autoimmune diseases. Pregnancy and breastfeeding require an individual assessment of the risks and should always be discussed with the treating doctor.<\/p>\n<\/div>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>The biofiller, also known as a plasma filler, is a gel made from the patient\u2019s own blood which treats wrinkles and restores volume without the use of synthetic additives.<\/p>","protected":false},"template":"","class_list":["post-590","glossary","type-glossary","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/4beauty-website-stage.247grad.de\/en\/wp-json\/wp\/v2\/glossary\/590","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/4beauty-website-stage.247grad.de\/en\/wp-json\/wp\/v2\/glossary"}],"about":[{"href":"https:\/\/4beauty-website-stage.247grad.de\/en\/wp-json\/wp\/v2\/types\/glossary"}],"wp:attachment":[{"href":"https:\/\/4beauty-website-stage.247grad.de\/en\/wp-json\/wp\/v2\/media?parent=590"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}